Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732949 | 0.84 | QPCT (0.61) | QPCTHDAC1HDAC8HDAC6 | |
| SCHEMBL12732681 | 0.78 | QPCT (0.62) | QPCTHDAC1HDAC8HDAC6 | |
| SCHEMBL22753763 | 0.78 | QPCT (0.62) | QPCTHDAC1HDAC8HDAC6 | |
| SCHEMBL12732942 | 0.75 | QPCT (0.51) | QPCTHRH3HDAC1HDAC8HDAC6 | |
| SCHEMBL12732947 | 0.75 | QPCT (0.52) | QPCTHRH3 | |
| SCHEMBL12732620 | 0.72 | QPCT (0.78) | QPCTHRH3 | |
| SCHEMBL12732689 | 0.70 | QPCT (0.54) | QPCTF10HDAC1HDAC8HDAC6 | |
| SCHEMBL12732940 | 0.68 | QPCT (0.52) | QPCTHRH3HDAC1HDAC8HDAC6 | |
| SCHEMBL12732938 | 0.68 | QPCT (0.49) | QPCTUSP2 | |
| SCHEMBL12805528 | 0.66 | QPCT (0.57) | QPCTHRH3AOC3MAPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029920-A1 | HETEROCYLCIC DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2011-03-17 | — | — | WO | disclosed |