SCHEMBL12818062

SCHEMBL12818062

CNC1=N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CNC3CCCCC3)O[C@@H]2S1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OGA O60502 13/20 0.64
HEXB P07686 3/20 0.64
HOGA1 Q86XE5 5/20 0.60
HEXA P06865 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15612356 0.99 OGA (0.63) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15612359 0.99 OGA (0.63) OGAHEXBHOGA1HEXA
SCHEMBL12819528 0.99 OGA (0.66) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15611196 0.98 OGA (0.64) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15611197 0.98 OGA (0.64) OGAHEXBHOGA1HEXA
SCHEMBL12819255 0.96 OGA (0.66) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15611609 0.95 OGA (0.64) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15611605 0.95 OGA (0.64) OGAHEXBHOGA1HEXA
SCHEMBL12965154 0.94 OGA (0.69) OGAHEXBHOGA1HEXA
Hydrochloric Acid SCHEMBL15611233 0.93 OGA (0.67) OGAHEXBHOGA1HEXA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9718854-B2 Selective glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2017-08-01 US claimed
EP-2691407-B1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2017-02-22 EP claimed
US-20140088028-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF PHARMARON BEIJING, CO. LTD. (CN) 2014-03-27 US claimed
EP-2691407-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Alectos Therapeutics Inc. (CA) 2014-02-05 EP claimed
WO-2012129802-A1 PYRANO[3,2-D]THIAZOL DERIVATIVES AND USES AS SELECTIVE GLYCOSIDASE INHIBITORS THEREOF ALECTOS THERAPEUTICS INC. (CA) 2012-10-04 WO claimed
WO-2012129651-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2012-10-04 WO claimed
US-9718854-B2 Selective glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2017-08-01 US disclosed
US-9718854-B2 Selective glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2017-08-01 US disclosed
US-9718854-B2 Selective glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2017-08-01 US disclosed
EP-2691407-B1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2017-02-22 EP disclosed
EP-2691407-B1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2017-02-22 EP disclosed
US-20140088028-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF PHARMARON BEIJING, CO. LTD. (CN) 2014-03-27 US disclosed
US-20140088028-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF PHARMARON BEIJING, CO. LTD. (CN) 2014-03-27 US disclosed
US-20140088028-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF PHARMARON BEIJING, CO. LTD. (CN) 2014-03-27 US disclosed
WO-2012129802-A1 PYRANO[3,2-D]THIAZOL DERIVATIVES AND USES AS SELECTIVE GLYCOSIDASE INHIBITORS THEREOF ALECTOS THERAPEUTICS INC. (CA) 2012-10-04 WO disclosed
WO-2012129651-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2012-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088028-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF OGA, ENGASE, GPI OGA 1/4885HEXB 53/4885HOGA1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.