SCHEMBL12819251

SCHEMBL12819251

O=C1CN(Cc2c(-c3cccs3)nc3ccc(-c4ccccc4)cn23)CCN1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 18/20 0.72
▸ SLC2A2 P11168 2/20 0.53
▸ NR1H4 Q96RI1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12819265 0.84 SLC2A1 (1.00) SLC2A1SLC2A2
SCHEMBL12819215 0.83 SLC2A1 (0.67) SLC2A1SLC2A2
SCHEMBL12818980 0.82 SLC2A1 (0.79) SLC2A1SLC2A2
SCHEMBL12819406 0.82 SLC2A1 (0.73) SLC2A1SLC2A2
SCHEMBL12818661 0.81 SLC2A1 (0.78) SLC2A1SLC2A2
SCHEMBL12819154 0.81 SLC2A1 (0.81) SLC2A1SLC2A2
SCHEMBL17718816 0.79 SLC2A1 (0.74) SLC2A1SLC2A2
SCHEMBL17718991 0.76 SLC2A1 (0.85) SLC2A1SLC2A2
SCHEMBL12818759 0.76 SLC2A1 (0.70) SLC2A1SLC2A2
SCHEMBL12819031 0.75 SLC2A1 (0.89) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2691392-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM Technology Transfer GmbH (DE) 2014-02-05 — — EP claimed
WO-2012130322-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY ELARA PHARMACEUTICALS GMBH (DE) 2012-10-04 — — WO claimed
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