SCHEMBL12819554

SCHEMBL12819554

Cc1cc(-c2ccc3nc(-c4ccc(Cl)cc4)c(CN4CCCN(C)CC4)n3c2)ccn1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 19/20 0.67
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ SLC2A3 P11169 1/20 0.51
▸ SLC2A4 P14672 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12819446 0.89 SLC2A1 (0.54) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12818838 0.89 SLC2A1 (0.52) SLC2A1MEN1KMT2A
SCHEMBL12819032 0.88 SLC2A1 (0.84) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12818848 0.88 SLC2A1 (0.70) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12818830 0.88 SLC2A1 (0.76) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12819124 0.87 SLC2A1 (0.77) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12818879 0.86 SLC2A1 (0.66) SLC2A1MEN1KMT2AKDM4EHTT
SCHEMBL12819133 0.86 SLC2A1 (0.74) SLC2A1MEN1KMT2A
SCHEMBL12818654 0.85 SLC2A1 (0.92) SLC2A1MEN1KMT2A
SCHEMBL12819159 0.84 SLC2A1 (0.55) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM TECHNOLOGY TRANSFER GMBH (DE) 2014-08-07 — — US claimed
EP-2691392-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM Technology Transfer GmbH (DE) 2014-02-05 — — EP claimed
WO-2012130322-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY ELARA PHARMACEUTICALS GMBH (DE) 2012-10-04 — — WO claimed
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM TECHNOLOGY TRANSFER GMBH (DE) 2014-08-07 — — US disclosed
EP-2691392-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM Technology Transfer GmbH (DE) 2014-02-05 — — EP disclosed
WO-2012130322-A1 IMIDAZO [1,2-A]PYRIDINE COMPOUNDS FOR USE IN THERAPY ELARA PHARMACEUTICALS GMBH (DE) 2012-10-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY HIF1A, HIF1AN, EGLN3 SLC2A1 1235/4885MEN1 3108/4885KMT2A 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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