Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820424 | 0.95 | POLB (0.79) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL2016778 | 0.90 | POLB (0.83) | POLBEPHX1GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL1999078 | 0.88 | POLB (0.80) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL10080421 | 0.86 | POLB (0.91) | POLBEPHX1GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL30473852 | 0.84 | POLB (0.88) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL13746134 | 0.82 | POLB (0.77) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL1437818 | 0.82 | POLB (0.77) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL7512372 | 0.82 | POLB (1.00) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL24423701 | 0.81 | POLB (0.69) | POLBEPHX1GABRPGABRDGABRA1 | |
| SCHEMBL3274450 | 0.81 | POLB (0.74) | POLBEPHX1EPHX2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012126084-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS | PHARMASCIENCE INC. (CA) | 2012-09-27 | — | — | WO | disclosed |
| WO-2011035417-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE FN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES | AEGERA THERAPEUTICS INC. (CA) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011035416-A1 | HSP90 MODULATING COMPOUNDS, COMPOSITIONS, METHODS AND USES | AEGERA THERAPEUTICS INC. (CA) | 2011-03-31 | — | — | WO | disclosed |