Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20888433 | 0.90 | EPHX1 (0.56) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL743999 | 0.84 | EPHX1 (0.65) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL12061480 | 0.84 | EPHX1 (0.65) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL215297 | 0.84 | EPHX1 (0.65) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL24827741 | 0.83 | EPHX1 (0.68) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL1128308 | 0.83 | EPHX1 (0.63) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL14768741 | 0.83 | EPHX1 (0.63) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL618966 | 0.81 | EPHX1 (0.66) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1061071 | 0.81 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL22759160 | 0.81 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362277-A | Benzamide compound containing imidazolone structure, and preparation method and application thereof | 沈阳药科大学 | 2024-01-09 | — | — | CN | disclosed |
| WO-2012126084-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS | PHARMASCIENCE INC. (CA) | 2012-09-27 | — | — | WO | disclosed |
| WO-2011035416-A1 | HSP90 MODULATING COMPOUNDS, COMPOSITIONS, METHODS AND USES | AEGERA THERAPEUTICS INC. (CA) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011035417-A1 | HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE FN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES | AEGERA THERAPEUTICS INC. (CA) | 2011-03-31 | — | — | WO | disclosed |