Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.52 |
| ▸ | F10 | P00742 | 10/20 | 0.52 |
| ▸ | PLG | P00747 | 8/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.52 |
| ▸ | TMPRSS11D | O60235 | 12/20 | 0.51 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289959 | 0.94 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL8290743 | 0.94 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL8290996 | 0.94 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL8289804 | 0.94 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL8289968 | 0.90 | F2 (0.52) | F2F10PLGKLKB1PROC | |
| SCHEMBL8290835 | 0.88 | F2 (0.59) | F2F10PLGKLKB1PROC | |
| SCHEMBL8291003 | 0.88 | F2 (0.64) | F2F10PLGKLKB1PROC | |
| SCHEMBL17366096 | 0.86 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL16843096 | 0.86 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL20117496 | 0.86 | F2 (0.57) | F2F10PLGKLKB1PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292640-A2 | Base-substituted benzylamine analogs for use as coagulation factor Xa inhibitors, the production and use thereof | The Medicines Company (Leipzig) GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |