Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825019 | 0.94 | SMO (0.44) | SMOEPHX2SSTR5 | |
| SCHEMBL12824862 | 0.94 | SMO (0.44) | SMOEPHX2SSTR5HDAC4SYK | |
| SCHEMBL12824720 | 0.94 | SMO (0.44) | SMOEPHX2SSTR5HDAC4SYK | |
| SCHEMBL12825057 | 0.94 | SMO (0.44) | SMOEPHX2SSTR5SLC6A5HDAC4 | |
| SCHEMBL12824616 | 0.93 | SMO (0.43) | SMOEPHX2SYK | |
| SCHEMBL12824594 | 0.93 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824858 | 0.91 | SMO (0.45) | SMOEPHX2SYK | |
| SCHEMBL12825022 | 0.90 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824713 | 0.90 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824615 | 0.89 | SMO (0.44) | SMOEPHX2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |