Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.49 |
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289817 | 0.90 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8289988 | 0.84 | F10 (0.45) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8289989 | 0.82 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8291002 | 0.82 | F10 (0.56) | F10F2PLGKLKB1PROC | |
| SCHEMBL8291001 | 0.82 | F10 (0.56) | F10F2PLGKLKB1PROC | |
| SCHEMBL8290739 | 0.80 | F2 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8290737 | 0.79 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8289990 | 0.79 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8289986 | 0.79 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8290838 | 0.78 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292640-A2 | Base-substituted benzylamine analogs for use as coagulation factor Xa inhibitors, the production and use thereof | The Medicines Company (Leipzig) GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |