SCHEMBL1282780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13735781	0.86	SMN1; SMN2 (0.50)	SMN1; SMN2CYP3A4CYP1A2CYP2C19NQO2
	SCHEMBL18038426	0.77	CYP3A4 (0.50)	SMN1; SMN2CYP3A4CYP1A2CYP2C19TSHR
	SCHEMBL34471465	0.75	CYP3A4 (0.45)	SMN1; SMN2CYP3A4CYP1A2CYP2C19NQO2
	SCHEMBL25339259	0.75	CYP3A4 (0.45)	SMN1; SMN2CYP3A4CYP1A2CYP2C19NQO2
	SCHEMBL29682132	0.75	CYP3A4 (0.45)	SMN1; SMN2CYP3A4CYP1A2CYP2C19NQO2
	SCHEMBL10464582	0.73	ADORA1 (0.47)	SMN1; SMN2CYP3A4CYP1A2CYP2C19TSHR
	SCHEMBL4141913	0.73	CYP3A4 (0.43)	SMN1; SMN2CYP3A4CA2CA4NQO2
	SCHEMBL4128227	0.72	NSD1 (0.46)	SMN1; SMN2CYP3A4CYP1A2CYP2C19CA2
	SCHEMBL1292197	0.71	NCOA1 (0.36)	SMN1; SMN2TSHRALDH1A1MAPTHSD17B10
	SCHEMBL1282532	0.69	ABL1 (0.51)	SMN1; SMN2PIK3CAPIK3CGRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.