⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829118 | 1.00 | — | — | |
| SCHEMBL11923422 | 1.00 | — | — | |
| SCHEMBL12828916 | 0.78 | — | — | |
| SCHEMBL12828961 | 0.78 | — | — | |
| SCHEMBL12828924 | 0.78 | — | — | |
| SCHEMBL14178162 | 0.77 | — | — | |
| SCHEMBL8171853 | 0.77 | — | — | |
| SCHEMBL12829102 | 0.74 | RNPEP (0.33) | — | |
| SCHEMBL12829095 | 0.74 | RNPEP (0.33) | — | |
| SCHEMBL12829109 | 0.74 | RNPEP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077279-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2011-03-31 | — | — | US | disclosed |
| WO-2010015447-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2009150007-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2009-12-17 | — | — | WO | disclosed |