Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NCS1 | P62166 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10189655 | 0.88 | CSNK1D (0.49) | DYRK1APOLBRIPK1NPC1RAB9A | |
| SCHEMBL11832198 | 0.83 | DYRK1A (0.50) | DYRK1ATRPV1CSNK1DCSNK1G2MAP3K5 | |
| SCHEMBL15451030 | 0.80 | DYRK1A (0.59) | DYRK1APOLBRIPK1NPC1RAB9A | |
| SCHEMBL4500811 | 0.78 | NPC1 (0.50) | DYRK1APOLBRIPK1NPC1RAB9A | |
| SCHEMBL3795843 | 0.78 | DYRK1A (0.60) | DYRK1APOLBRIPK1NPC1RAB9A | |
| SCHEMBL4513162 | 0.77 | POLB (0.49) | DYRK1APOLBRIPK1NPC1RAB9A | |
| SCHEMBL18233043 | 0.77 | NPC1 (0.60) | DYRK1APOLBNPC1RAB9ACSNK1D | |
| SCHEMBL9883988 | 0.77 | DYRK1A (0.78) | DYRK1ANPC1RAB9AMAP3K5SMN1; SMN2 | |
| SCHEMBL14791428 | 0.76 | NPC1 (0.59) | DYRK1ATRPV1NPC1RAB9AHDAC3 | |
| SCHEMBL1913774 | 0.74 | NPC1 (0.61) | DYRK1APOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | MAP3K20, MAP3K1, PDPK1 | DYRK1A 673/4885TRPV1 3586/4885POLB 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.