SCHEMBL12830241

SCHEMBL12830241

C=C(OC(C)(C)C)N(CC1CC1)c1cc(Cl)nc2c(/C=C3\CC(=O)NC3=O)cnn12

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK2B P67870 1/20 0.39
GPR119 Q8TDV5 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486070 0.91 CSNK2B (0.40) CSNK2BGPR119
SCHEMBL1486069 0.91 CSNK2B (0.40) CSNK2BGPR119
SCHEMBL1486088 0.81 CSNK2B (0.41) CSNK2BGPR119
SCHEMBL1486086 0.81 CSNK2B (0.41) CSNK2BGPR119
SCHEMBL12840997 0.80
SCHEMBL1486098 0.77 CSNK2B (0.48) CSNK2B
SCHEMBL12583401 0.76 CSNK2B (0.35) CSNK2B
SCHEMBL1486099 0.73 CSNK2B (0.47) CSNK2BGPR119
SCHEMBL12768833 0.73 CSNK2B (0.47) CSNK2BGPR119
SCHEMBL15739950 0.70 ACACB (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011031979-A1 PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS CYLENE PHARMACEUTICALS INC. (US) 2011-03-17 WO disclosed