Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433592 | 0.92 | ABL1 (0.39) | ABL1 | |
| SCHEMBL3435008 | 0.91 | ABL1 (0.38) | ABL1 | |
| SCHEMBL3432375 | 0.81 | CETP (0.36) | — | |
| SCHEMBL3432980 | 0.79 | PIK3CD (0.38) | — | |
| SCHEMBL2132036 | 0.78 | — | — | |
| SCHEMBL1505517 | 0.77 | — | — | |
| SCHEMBL2134989 | 0.77 | — | — | |
| SCHEMBL1505568 | 0.76 | ABL1 (0.42) | ABL1 | |
| SCHEMBL3488070 | 0.76 | — | — | |
| SCHEMBL2133971 | 0.75 | FGFR3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024004-A1 | HETEROCYCLIC UREA DERIVATIVES USEFUL FOR TREATMENT OF BACTERIAL INFECTION | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2009106885-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |