Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SF3B3 | Q15393 | 10/20 | 0.71 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905749 | 0.92 | SF3B3 (0.76) | SF3B3HMGCR | |
| SCHEMBL12877481 | 0.92 | SF3B3 (0.76) | SF3B3HMGCR | |
| SCHEMBL30311586 | 0.92 | SF3B3 (0.76) | SF3B3HMGCR | |
| SCHEMBL12877318 | 0.92 | SF3B3 (0.76) | SF3B3HMGCR | |
| SCHEMBL14539614 | 0.92 | SF3B3 (0.76) | SF3B3HMGCR | |
| SCHEMBL3280402 | 0.91 | SF3B3 (0.77) | SF3B3HMGCR | |
| SCHEMBL12877475 | 0.91 | SF3B3 (0.77) | SF3B3HMGCR | |
| SCHEMBL1505114 | 0.91 | SF3B3 (0.71) | SF3B3 | |
| SCHEMBL1505026 | 0.91 | SF3B3 (0.70) | SF3B3HMGCR | |
| SCHEMBL3626171 | 0.91 | SF3B3 (0.70) | SF3B3HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292610-A1 | Macrolides with VEGF transcription suppression activity | MERCIAN CORPORATION (JP) | 2011-03-09 | — | — | EP | disclosed |