Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 12/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508051 | 0.86 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL14229524 | 0.81 | KCNN4 (0.47) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL1508053 | 0.78 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL1508111 | 0.76 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL1507860 | 0.75 | KCNN4 (0.56) | KCNN4KCNE1KCNQ1KIF11 | |
| SCHEMBL1508118 | 0.75 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL14229961 | 0.75 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL5434711 | 0.73 | KCNN4 (0.40) | KCNN4KCNE1KCNQ1KIF11MLNR | |
| SCHEMBL12834748 | 0.73 | KCNN4 (0.54) | KCNN4KCNE1KCNQ1KIF11 | |
| SCHEMBL1507917 | 0.70 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1KIF11NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292595-A1 | Potassium channel modulators | NeuroSearch AS (DK) | 2011-03-09 | — | — | EP | disclosed |