Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508041 | 0.79 | MAPT (0.44) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL8253229 | 0.75 | MAPT (0.44) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL18112130 | 0.74 | MAPT (0.43) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL1508044 | 0.72 | MAPT (0.36) | MAPTALDH1A1 | |
| SCHEMBL27669587 | 0.69 | MAPT (0.39) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL14155056 | 0.69 | MAPT (0.39) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL13398120 | 0.69 | EPHX2 (0.40) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL2764401 | 0.69 | MAPT (0.38) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL9855275 | 0.68 | MAPT (0.43) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL7682222 | 0.68 | KCNN4 (0.45) | MAPTKMT2AMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292595-A1 | Potassium channel modulators | NeuroSearch AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| EP-1911740-A1 | POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2008-04-16 | — | — | EP | disclosed |