Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267927 | 1.00 | CYP1A2 (0.42) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL1268152 | 1.00 | CYP1A2 (0.42) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL3971244 | 1.00 | CYP1A2 (0.42) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL178642 | 1.00 | CYP1A2 (0.42) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL1267911 | 0.87 | NR1H2 (0.38) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL1268168 | 0.87 | NR1H2 (0.38) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL3964957 | 0.87 | NR1H2 (0.38) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL15909556 | 0.82 | NR1H2 (0.49) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL1722772 | 0.82 | CYP1A2 (0.45) | CYP1A2POLBCYP3A4CYP2C19CHRM2 | |
| SCHEMBL20371652 | 0.82 | CYP1A2 (0.45) | CYP1A2POLBCYP3A4CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031745-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |