SCHEMBL128378

SCHEMBL128378

[CH2]OCC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7858286 0.79
SCHEMBL7859392 0.69
SCHEMBL125228 0.69
SCHEMBL20100 0.69
SCHEMBL131288 0.67
SCHEMBL28645602 0.67
SCHEMBL2589144 0.67
SCHEMBL129334 0.65
SCHEMBL25284832 0.65
SCHEMBL7431682 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
WO-2024118887-A1 N-PHENYL-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS WILD TYPE C-KIT KINASE INHIBITORS FOR THE TREATMENT OF URTICARIA BLUEPRINT MEDICINES CORPORATION (US) 2024-06-06 WO claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 EP claimed
WO-2022200208-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2022-09-29 WO claimed
US-20220153754-A1 FUSED HETEROCYCLE DERIVATIVES AS CAPSID ASSEMBLY MODULATORS Janssen Sciences Ireland Unlimited Company (IE) 2022-05-19 US claimed
EP-3976619-A1 FUSED HETEROCYCLE DERIVATIVES AS CAPSID ASSEMBLY MODULATORS Janssen Sciences Ireland Unlimited Company (IE) 2022-04-06 EP claimed
CN-113906031-A Fused heterocyclic derivatives as capsid assembly modulators 爱尔兰詹森科学公司 2022-01-07 CN claimed
CN-113906030-A Fused heterocyclic derivatives 爱尔兰詹森科学公司 2022-01-07 CN claimed
US-20200390100-A1 SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES BAYER AG (DE) 2020-12-17 US claimed
WO-2020239864-A1 FUSED HETEROCYCLE DERIVATIVES AS CAPSID ASSEMBLY MODULATORS Janssen Sciences Ireland Unlimited Company (IE) 2020-12-03 WO claimed
CN-100456933-C Herbicidal composition containing benzoylcyclohexanediones and safeners BAYER CROPSCIENCE AG (DE) 2009-02-04 CN claimed
US-7101827-B2 Herbicides comprising benzoylcyclohexanediones and safeners AVENTIS CROPSCIENCE GMBH (DE) 2006-09-05 US claimed
EP-1383382-B1 HERBICIDAL AGENT COMPRISING BENZOYLCYCLOHEXANEDIONES AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2006-03-08 EP claimed
US-6884757-B2 Herbicides comprising benzoylcyclohexanediones and safeners AVENTIS CROPSCIENCE GMBH (DE) 2005-04-26 US claimed
US-20040224848-A1 Herbicides comprising benzoylcyclohexanediones and safeners AVENTIS CROPSCIENCE GMBH (DE) 2004-11-11 US claimed
US-20040224849-A1 Herbicides comprising benzoylcyclohexanediones and safeners BAYER CROPSCIENCE GMBH (DE) 2004-11-11 US claimed
CN-1503626-A Herbicidal composition containing benzoylcyclohexanediones and safeners �Ϻ���ͨ��ѧ 2004-06-09 CN claimed
EP-1383382-A2 HERBICIDAL AGENT COMPRISING BENZOYLCYCLOHEXANEDIONES AND SAFENERS Bayer CropScience GmbH (DE) 2004-01-28 EP claimed
US-20030078167-A1 Herbicides comprising benzoylcyclohexanediones and safeners BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-04-24 US claimed
WO-2002085120-A2 HERBICIDAL AGENT COMPRISING BENZOYLCYCLOHEXANEDIONES AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2002-10-31 WO claimed