SCHEMBL12846337

SCHEMBL12846337

OCC1O[C@@H](OC2C(O)C(O)(O)O[C@@H]2CO)C(O)C(O)[C@@H]1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.74
▸ KMT2A Q03164 2/20 0.74
▸ LGALS8 O00214 1/20 0.46
▸ LGALS3 P17931 1/20 0.46
▸ LGALS4 P56470 1/20 0.46
▸ PTPN1 P18031 2/20 0.46
▸ GJA1 P17302 1/20 0.45
▸ GJB2 P29033 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ SYNJ2 O15056 1/20 0.44
▸ TYR P14679 1/20 0.43
▸ CDK1 P06493 1/20 0.42
▸ CCNB1 P14635 1/20 0.42
▸ IGF2R P11717 1/20 0.41
▸ FGF1 P05230 1/20 0.41
▸ FGF2 P09038 1/20 0.41
▸ VEGFA P15692 1/20 0.41
▸ HPSE Q9Y251 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157303 0.90 MEN1 (0.64) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL15942980 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL15942982 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL17623952 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL12787176 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL11892653 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL18479188 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL17241809 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
Lactulose SCHEMBL11890264 0.85 MEN1 (1.00) MEN1KMT2ALGALS8LGALS3LGALS4
SCHEMBL6823456 0.85 MEN1 (0.70) MEN1KMT2ALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110060139-A1 CARBOHYDRATE DERIVATIVES GLYCOM A/S (DK) 2011-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060139-A1 CARBOHYDRATE DERIVATIVES ALG1, MAN2A1, MAN1B1 MEN1 131/4885KMT2A 2534/4885LGALS8 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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