Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.64 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.64 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.64 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | S100A4 | P26447 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849477 | 0.86 | MEN1 (0.67) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL17573922 | 0.81 | MEN1 (0.60) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL3500025 | 0.80 | MEN1 (0.97) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL3034016 | 0.80 | MEN1 (0.64) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL3037436 | 0.80 | MEN1 (0.64) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL29155892 | 0.80 | MEN1 (0.64) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL6391113 | 0.79 | MEN1 (0.75) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL15101231 | 0.79 | KMT2A (0.67) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL3505138 | 0.79 | MEN1 (1.00) | MEN1KMT2APOLBUSP2TNNI3 | |
| SCHEMBL3502339 | 0.77 | MEN1 (0.77) | MEN1KMT2APOLBUSP2TNNI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031330-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | ENZO LIFE SCIENCES, INC. (US) | 2011-03-17 | — | — | WO | disclosed |