⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843249 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL6663196 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL21404983 | 0.86 | TSHR (0.30) | — | |
| Zinc Ion SCHEMBL25253083 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL6456965 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL25300512 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL21405223 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL20490117 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL3176617 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL10324906 | 0.86 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143169-B1 | PROCESSES FOR THE PREPARATION OF A KINASE INHIBITOR | EXELIXIS INC (US) | 2026-04-15 | — | — | EP | claimed |
| CN-121571089-A | Dynamic explosion-eliminating tubular reaction system and method for nitramine energetic material | 西安近代化学研究所 | 2026-02-27 | — | — | CN | claimed |
| US-12497367-B2 | Processes for the preparation of a kinase inhibitor | EXELIXIS, INC. (US) | 2025-12-16 | — | — | US | claimed |
| CN-120025542-A | Non-isocyanate polyurethane and multicomponent selective synthesis method thereof | 华南理工大学 | 2025-05-23 | — | — | CN | claimed |
| CN-119978387-A | Three-component synthesis method of polyphosphonate | 华南理工大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119874783-A | Deep blue light emitting triazole carbene iridium complex, synthesis method thereof and application thereof in electroluminescent device | 香港理工大学深圳研究院 | 2025-04-25 | — | — | CN | claimed |
| CN-119613701-A | Method for synthesizing functionalized polyether in multi-proton system | 华南理工大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119409701-A | Preparation method and application of blue light iridium (III) complex containing triazole carbene auxiliary ligand | 成都大学 | 2025-02-11 | — | — | CN | claimed |
| US-20240376024-A1 | METHOD FOR PREPARING DEUTERATED CHEMICAL BY MEANS OF DEUTERATION REACTION OF CARBON-HYDROGEN BOND WITH DEUTERIUM GAS UNDER CATALYSIS OF ALKALI | FUDAN UNIVERSITY (CN) | 2024-11-14 | — | — | US | claimed |
| CN-116003771-B | Synthesis method of alpha, beta-unsaturated carboxylic ester functionalized polymer | 华南理工大学 | 2024-10-01 | — | — | CN | claimed |
| EP-1678135-B1 | PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-05-13 | — | — | EP | claimed |
| EP-2054379-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE | Alembic Limited (IN) | 2009-05-06 | — | — | EP | claimed |
| WO-2008101860-A1 | NOVEL PROCESS FOR THE PREPARATION OF 5-(4-CHLOROPHENYL)-1-(2,4-DICHLOROPHENYL)-4-METHYL-N-(PIPERIDIN-1-YL)PYRAZOLE-3-CARBOXAMIDE | SANDOZ AG (CH) | 2008-08-28 | — | — | WO | claimed |
| WO-2008062432-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE | ALEMBIC LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |
| US-20060258877-A1 | Process for the preparation of (E)-2-cyano-3-(3, 4-dihydroxy-5-nitrophenyl)-N, N-diethyl-2-propenamide (entacapone) | ALEMBIC LIMITED (IN) | 2006-11-16 | — | — | US | claimed |
| US-7112682-B2 | Process for the preparation of N-amino substituted heterocyclic compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2006-09-26 | — | — | US | claimed |
| EP-1678135-A1 | PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS | Aventis Pharmaceuticals, Inc. (US) | 2006-07-12 | — | — | EP | claimed |
| US-20050101654-A1 | Process for the preparation of N-amino substituted heterocyclic compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-12 | — | — | US | claimed |
| WO-2005035496-A1 | PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-04-21 | — | — | WO | claimed |
| EP-1081144-A2 | Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | claimed |