⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533547 | 0.67 | — | — | |
| SCHEMBL514440 | 0.67 | — | — | |
| SCHEMBL13716823 | 0.67 | — | — | |
| SCHEMBL516140 | 0.67 | — | — | |
| SCHEMBL776440 | 0.67 | — | — | |
| SCHEMBL16811819 | 0.64 | — | — | |
| SCHEMBL14304345 | 0.64 | — | — | |
| SCHEMBL8281705 | 0.64 | — | — | |
| Fluoride SCHEMBL777351 | 0.64 | — | — | |
| Fluoride SCHEMBL778559 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280000-A1 | COMPOUND HAVING NPY Y5 RECEPTOR ANTAGONIST ACTIVITY | Shionogi&Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
| EP-2017261-A1 | AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONIST ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2009-01-21 | — | — | EP | disclosed |