Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856004 | 0.89 | MEN1 (0.63) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679815 | 0.89 | MEN1 (0.63) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679827 | 0.88 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679826 | 0.88 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679828 | 0.88 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679825 | 0.88 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679813 | 0.86 | MEN1 (0.63) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679658 | 0.86 | MEN1 (0.67) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679671 | 0.85 | MEN1 (0.65) | MEN1KMT2AKDM4ENPC1MITF | |
| SCHEMBL12679674 | 0.85 | MEN1 (0.65) | MEN1KMT2AKDM4ENPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279732-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2011-02-02 | — | — | EP | disclosed |