Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 8/20 | 0.76 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.62 |
| ▸ | JAK3 | P52333 | 3/20 | 0.57 |
| ▸ | ULK1 | O75385 | 1/20 | 0.55 |
| ▸ | KIF15 | Q9NS87 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080462 | 0.86 | RAF1 (0.76) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1394836 | 0.86 | RAF1 (1.00) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1395408 | 0.86 | RAF1 (0.76) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1394837 | 0.86 | RAF1 (1.00) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1395177 | 0.77 | RAF1 (0.77) | RAF1TLK2JAK3KIF15LRRK2 | |
| SCHEMBL1395178 | 0.77 | RAF1 (0.77) | RAF1TLK2JAK3KIF15LRRK2 | |
| SCHEMBL5084106 | 0.76 | RAF1 (0.67) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1394705 | 0.76 | RAF1 (0.67) | RAF1TLK2JAK3ULK1KIF15 | |
| SCHEMBL1394700 | 0.76 | RAF1 (0.80) | RAF1TLK2ULK1KIF15LRRK2 | |
| SCHEMBL5080490 | 0.76 | RAF1 (0.80) | RAF1TLK2ULK1KIF15LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |