Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.97 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385390 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL11516130 | 0.74 | NPSR1 (0.79) | SMN1; SMN2NPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL11102433 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1ALDH1A1LMNATSHR | |
| SCHEMBL25831437 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1LMNATSHRPKM | |
| SCHEMBL17284616 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL7797340 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL17271755 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL15779844 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1ALDH1A1LMNATSHR | |
| SCHEMBL7797307 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1ALDH1A1THRBTSHR | |
| SCHEMBL7797298 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | WARATAH PHARMACEUTICALS INC. (CA) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028719-A1 | SCREENING METHODS FOR AMYLOID BETA MODULATORS | APP, BACE1, IAPP | SMN1; SMN2 2222/4885NPSR1 1086/4885CHRM2 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.