SCHEMBL1286400

SCHEMBL1286400

Nc1cccc(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
GAA P10253 1/20 0.48
MMP2 P08253 1/20 0.39
HSP90AA1 P07900 1/20 0.38
NTSR1 P30989 1/20 0.38
CD44 P16070 1/20 0.37
HDAC3 O15379 1/20 0.36
MAPK1 P28482 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
CASP7 P55210 2/20 0.36
ALOX15 P16050 2/20 0.36
CYP3A4 P08684 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
G6PD P11413 1/20 0.35
CASP6 P55212 1/20 0.35
TSHR P16473 1/20 0.34
PBRM1 Q86U86 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27955730 0.85 MAPT (0.59) MAPTGAAMMP2HSP90AA1NTSR1
Benzene SCHEMBL28303083 0.78 MAPT (0.74) MAPTGAAMMP2PBRM1ALDH1A1
SCHEMBL636319 0.78 MAPT (0.47) MAPTGAAMMP2CD44HDAC3
SCHEMBL7160188 0.78 MAPT (0.47) MAPTGAAMMP2CD44HDAC3
SCHEMBL112508 0.78 MAPT (0.74) MAPTGAAMMP2PBRM1ALDH1A1
SCHEMBL29786713 0.78 MAPT (0.74) MAPTGAAMMP2PBRM1ALDH1A1
SCHEMBL985155 0.78 MAPT (0.52) MAPTGAAMMP2CD44HDAC3
Benzoic Acid SCHEMBL28341632 0.76 MAPT (0.55) MAPTGAAMMP2CASP7ALOX15
SCHEMBL1885623 0.76 MAPT (0.55) MAPTGAAMMP2HDAC3MAPK1
SCHEMBL28282156 0.76 MAPT (0.71) MAPTGAAMMP2PBRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625365-B1 VACUUM INSULATED GLASS (VIG) UNIT INCLUDING NANO-COMPOSITE PILLARS, AND/OR METHODS OF MAKING THE SAME GUARDIAN GLASS LLC (US) 2020-06-17 EP disclosed
US-10590695-B2 Vacuum insulated glass (VIG) unit including nano-composite pillars, and/or methods of making the same GUARDIAN GLASS, LLC. (US) 2020-03-17 US disclosed
US-20170268286-A1 VACUUM INSULATED GLASS (VIG) UNIT INCLUDING NANO-COMPOSITE PILLARS, AND/OR METHODS OF MAKING THE SAME GUARDIAN GLASS, LLC. 2017-09-21 US disclosed
US-8679271-B2 Vacuum insulated glass (VIG) unit including nano-composite pillars, and/or methods of making the same GUARDIAN INDUSTRIES CORP. (US) 2014-03-25 US disclosed
US-8679598-B2 Vacuum insulated glass (VIG) unit including nano-composite pillars, and/or methods of making the same GUARDIAN INDUSTRIES CORP. (US) 2014-03-25 US disclosed
EP-2625365-A1 VACUUM INSULATED GLASS (VIG) UNIT INCLUDING NANO-COMPOSITE PILLARS, AND/OR METHODS OF MAKING THE SAME Guardian Industries Corp. (US) 2013-08-14 EP disclosed
US-20130136875-A1 VACUUM INSULATED GLASS (VIG) UNIT INCLUDING NANO-COMPOSITE PILLARS, AND/OR METHODS OF MAKING THE SAME GUARDIAN INDUSTRIES CORP. (US) 2013-05-30 US disclosed
US-20120088045-A1 Vacuum insulated glass (VIG) unit including nano-composite pillars, and/or methods of making the same GUARDIAN INDUSTRIES CORP. (US) 2012-04-12 US disclosed
WO-2012047250-A1 VACUUM INSULATED GLASS (VIG) UNIT INCLUDING NANO-COMPOSITE PILLARS, AND/OR METHODS OF MAKING THE SAME GUARDIAN INDUSTRIES CORP. (US) 2012-04-12 WO disclosed