SCHEMBL12866186

SCHEMBL12866186

C[N+]1=C(/C=C/C=C/C=C/c2ccc(O)c(O)c2)C(C)(C)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
APP P05067 2/20 0.48
MEN1 O00255 4/20 0.44
LMNA P02545 4/20 0.44
KMT2A Q03164 4/20 0.44
HTT P42858 3/20 0.44
MMP14 P50281 1/20 0.44
ALDH1A1 P00352 3/20 0.44
THRB P10828 3/20 0.44
RECQL P46063 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
XDH P47989 1/20 0.43
VDR P11473 4/20 0.41
NPC1 O15118 2/20 0.40
S1PR4 O95977 2/20 0.40
POLB P06746 2/20 0.40
ALPG P10696 2/20 0.40
PKM P14618 2/20 0.40
S1PR1 P21453 2/20 0.40
NTSR1 P30989 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866128 0.91 MAPT (0.57) MAPTAPPMEN1LMNAKMT2A
SCHEMBL17994892 0.80 MAPT (0.57) MAPTAPPMEN1LMNAKMT2A
SCHEMBL13844392 0.79 MAPT (0.55) MAPTAPPMEN1LMNAKMT2A
SCHEMBL17994913 0.79 MAPT (0.53) MAPTAPPMEN1LMNAKMT2A
SCHEMBL13005206 0.77 PTPN1 (0.56) MAPTAPPMEN1LMNAKMT2A
SCHEMBL1405400 0.77 APP (0.53) MAPTAPPMEN1LMNAKMT2A
SCHEMBL1405401 0.77 APP (0.53) MAPTAPPMEN1LMNAKMT2A
SCHEMBL25664248 0.76 MAPT (0.72) MAPTAPPMEN1LMNAKMT2A
SCHEMBL12866084 0.76 MAPT (0.50) MAPTAPPMEN1LMNAKMT2A
SCHEMBL11988995 0.76 MAPT (0.64) MAPTAPPMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed