SCHEMBL12866187

SCHEMBL12866187

CN1/C(=C\C=C2/CCCC(/C=C/c3ccc(O)c(O)c3)=C2Cl)C(C)(C)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.44
MAPT P10636 13/20 0.41
HTT P42858 7/20 0.41
LMNA P02545 4/20 0.41
MEN1 O00255 11/20 0.40
KMT2A Q03164 11/20 0.40
KDM4E B2RXH2 7/20 0.40
GAA P10253 4/20 0.40
POLB P06746 4/20 0.40
ALDH1A1 P00352 4/20 0.40
RECQL P46063 4/20 0.40
CRHBP P24387 2/20 0.39
CRHR2 Q13324 2/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
USP2 O75604 4/20 0.39
THRB P10828 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21923274 0.80 HTT (0.49) APPMAPTHTTLMNAMEN1
SCHEMBL12976316 0.79 GAA (0.35) APPMAPTKDM4EGAARAB9A
SCHEMBL13928996 0.78 MAPT (0.45) APPMAPTHTTLMNAMEN1
SCHEMBL22489411 0.78 MAPT (0.45) APPMAPTHTTLMNAMEN1
SCHEMBL7604087 0.78 MAPT (0.45) APPMAPTHTTLMNAMEN1
SCHEMBL766931 0.78 MAPT (0.45) APPMAPTHTTLMNAMEN1
SCHEMBL3131736 0.78 MAPT (0.45) APPMAPTHTTLMNAMEN1
SCHEMBL13928997 0.77 APP (0.43) APPMAPTHTTLMNAMEN1
Iodide SCHEMBL23668383 0.77 MAPT (0.45) APPMAPTHTTLMNAMEN1
Iodide SCHEMBL1156819 0.77 MAPT (0.45) APPMAPTHTTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed