⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360134 | 0.86 | — | — | |
| SCHEMBL10710215 | 0.80 | — | — | |
| SCHEMBL133947 | 0.80 | — | — | |
| SCHEMBL677683 | 0.76 | — | — | |
| SCHEMBL4326201 | 0.76 | — | — | |
| SCHEMBL10486802 | 0.76 | — | — | |
| SCHEMBL26833286 | 0.76 | — | — | |
| SCHEMBL9785074 | 0.76 | — | — | |
| SCHEMBL15785134 | 0.75 | — | — | |
| SCHEMBL2922806 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056878-B2 | Hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-16 | — | — | US | disclosed |
| US-8921449-B2 | Hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140296554-A1 | HYDROLYSIS-RESISTANT SILICONE COMPOUNDS | JOHNSON & JOHNSON VISION CARE (US) | 2014-10-02 | — | — | US | disclosed |
| US-8779178-B2 | Hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130131298-A1 | HYDROLYSIS-RESISTANT SILICONE COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130131369-A1 | HYDROLYSIS-RESISTANT SILICONE COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8357818-B2 | Hydrolysis-resistant silicone compounds | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-01-22 | — | — | US | disclosed |
| US-20110028673-A1 | HYDROLYSIS-RESISTANT SILICONE COMPOUNDS | JOHNSON & JOHNSON VISION CARE, INC. | 2011-02-03 | — | — | US | disclosed |
| US-7838698-B2 | Such as 3-[tris(butyldimethylsiloxy)silyl]propyl methacrylate; sterically hindered, purity; molded copolymers; contact lenses, intraocular lenses, artificial cornea, eyeglasses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-11-23 | — | — | US | disclosed |
| US-20080081894-A1 | Such as 3-[tris(butyldimethylsiloxy)silyl]propyl methacrylate; sterically hindered, purity; molded copolymers; contact lenses, intraocular lenses, artificial cornea, eyeglasses | JOHNSON & JOHNSON VISION CARE, INC. | 2008-04-03 | — | — | US | disclosed |