Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.54 |
| ▸ | KDM5C | P41229 | 4/20 | 0.54 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287060 | 0.86 | KDM4C (0.41) | KDM4CKDM5CPROKR1GRM2KDM6B | |
| SCHEMBL17144425 | 0.83 | KDM4C (0.56) | KDM4CKDM5CPROKR1KDM2BKDM6B | |
| SCHEMBL17144627 | 0.83 | KDM4C (0.56) | KDM4CKDM5CPROKR1KDM2BKDM6B | |
| SCHEMBL19741668 | 0.80 | KDM4C (0.55) | KDM4CKDM5CKDM2BKDM6BKDM2A | |
| SCHEMBL17144210 | 0.78 | KDM4C (0.59) | KDM4CKDM5CKDM2BPIK3CAKDM6B | |
| SCHEMBL19741723 | 0.77 | KDM4C (0.49) | KDM4CKDM5CPROKR1KDM6BKDM2A | |
| SCHEMBL17144580 | 0.77 | KDM4C (0.49) | KDM4CKDM5CPROKR1KDM6BKDM2A | |
| SCHEMBL17144601 | 0.77 | KDM4C (0.49) | KDM4CKDM5CPROKR1KDM6BKDM2A | |
| SCHEMBL17144386 | 0.77 | KDM4C (0.49) | KDM4CKDM5CPROKR1KDM2BKDM6B | |
| SCHEMBL2305288 | 0.74 | KDM4C (0.76) | KDM4CKDM5CKDM2BPIK3CAKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047156-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS PLASMINOGEN INHIBITORS AND THEIR USE IN THE TREATMENT OF FIBRINOLYSIS RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-04-12 | — | — | WO | disclosed |