Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947971 | 0.87 | TSHR (0.48) | IDO1AGXTAPP | |
| SCHEMBL7888039 | 0.85 | IDO1 (0.64) | IDO1AGXTMAOBAPPLOXL2 | |
| SCHEMBL7219594 | 0.78 | IDO1 (0.56) | IDO1AGXTMAOBAPPTAAR1 | |
| Hydroxyamine SCHEMBL8923579 | 0.78 | IDO1 (0.62) | IDO1AGXTMAOBAPPLOXL2 | |
| SCHEMBL22304854 | 0.78 | IDO1 (0.56) | IDO1AGXTMAOBAPPLOXL2 | |
| SCHEMBL6542140 | 0.77 | TAAR1 (0.46) | IDO1AGXTMAOBLOXL2TAAR1 | |
| SCHEMBL4343354 | 0.76 | TSHR (0.71) | IDO1AGXT | |
| SCHEMBL7213285 | 0.76 | AGXT (0.54) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL883828 | 0.76 | IDO1 (0.54) | IDO1AGXTMAOBAPPLOXL2 | |
| Hydrochloric Acid SCHEMBL29116870 | 0.76 | IDO1 (0.58) | IDO1AGXTMAOBAPPLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |