Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679187 | 1.00 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468130 | 1.00 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468129 | 1.00 | PTPRB (1.00) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL468195 | 0.99 | PTPRB (0.98) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL6117471 | 0.99 | PTPRB (0.98) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL468198 | 0.99 | PTPRB (0.98) | PTPRB | |
| SCHEMBL680192 | 0.92 | PTPRB (1.00) | PTPRB | |
| SCHEMBL468317 | 0.92 | PTPRB (1.00) | PTPRB | |
| Ammonia Solution, Strong SCHEMBL16030961 | 0.91 | PTPRB (0.98) | PTPRB | |
| SCHEMBL19575842 | 0.91 | PTPRB (0.83) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624916-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | Aerpio Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2012047966-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | AKEBIA THERAPEUTICS INC. (US) | 2012-04-12 | — | — | WO | claimed |