Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467973 | 0.92 | PTPRB (0.71) | PTPRB | |
| SCHEMBL468246 | 0.91 | PTPRB (0.66) | PTPRB | |
| SCHEMBL3926682 | 0.90 | PTPRB (0.65) | PTPRB | |
| SCHEMBL680027 | 0.90 | PTPRB (0.65) | PTPRB | |
| SCHEMBL680026 | 0.90 | PTPRB (0.65) | PTPRB | |
| SCHEMBL679603 | 0.87 | PTPRB (0.72) | PTPRB | |
| SCHEMBL679604 | 0.87 | PTPRB (0.72) | PTPRB | |
| SCHEMBL21670804 | 0.84 | PTPRB (0.70) | PTPRB | |
| SCHEMBL679639 | 0.84 | PTPRB (0.70) | PTPRB | |
| SCHEMBL679638 | 0.84 | PTPRB (0.70) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624916-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | Aerpio Therapeutics Inc. (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2012047966-A2 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | AKEBIA THERAPEUTICS INC. (US) | 2012-04-12 | — | — | WO | claimed |
| EP-2967066-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | Aerpio Therapeutics Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145068-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | AERPIO THERAPEUTICS INC. (US) | 2014-09-18 | — | — | WO | disclosed |