SCHEMBL12875490

SCHEMBL12875490

O=C(Nc1ccc(Cl)cc1)Nc1ccc2c(c1)B(O)OC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 17/20 1.00
CA2 P00918 17/20 1.00
CA12 O43570 13/20 0.78
CA9 Q16790 13/20 0.78
CA4 P22748 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12875785 0.88 CA1 (0.79) CA1CA2CA12CA9CA4
SCHEMBL12875128 0.88 CA1 (0.78) CA1CA2CA12CA9CA4
SCHEMBL12875486 0.88 CA1 (0.80) CA1CA2CA12CA9CA4
SCHEMBL596690 0.88 CA1 (1.00) CA1CA2CA12CA9CA4
SCHEMBL2280424 0.87 CA1 (0.78) CA1CA2CA12CA9CA4
SCHEMBL12875294 0.86 CA1 (0.78) CA1CA2CA12CA9CA4
SCHEMBL12875317 0.86 CA1 (1.00) CA1CA2CA12CA9CA4
SCHEMBL12875790 0.86 CA1 (0.75) CA1CA2CA12CA9CA4
SCHEMBL12875406 0.85 CA1 (0.76) CA1CA2CA12CA9CA4
SCHEMBL2285669 0.84 CA1 (0.72) CA1CA2CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011019612-A1 BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS ANACOR PHARMACEUTICALS, INC. (US) 2011-02-17 WO disclosed