Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.60 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17403045 | 1.00 | KDM1A (0.60) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL883113 | 0.81 | KDM1A (0.68) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL12295868 | 0.81 | KDM1A (0.68) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL3673574 | 0.77 | HTR2A (0.52) | KDM1AHTR2CHTR2BCYP2C9CYP3A4 | |
| SCHEMBL12714992 | 0.77 | KDM1A (0.62) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL24658830 | 0.77 | KDM1A (0.62) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| Bicarbonate SCHEMBL11486402 | 0.76 | KDM1A (0.46) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL12808654 | 0.75 | MEN1 (0.40) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL14101959 | 0.75 | KDM1A (0.60) | KDM1AHTR2CHTR2B | |
| SCHEMBL21503486 | 0.75 | KDM1A (0.60) | KDM1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021645-A1 | BICYCLIC UREA DERIVATIVE OR PHARMACOLOGICALLY PERMITTED SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2011-02-24 | — | — | WO | disclosed |