Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.68 |
| ▸ | CDK2 | P24941 | 3/20 | 0.68 |
| ▸ | IGF1R | P08069 | 7/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164993 | 0.93 | CCNA2 (0.66) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784422 | 0.90 | CCNA2 (0.63) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12878463 | 0.89 | CCNA2 (0.74) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12878269 | 0.85 | CCNA2 (0.66) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12783887 | 0.85 | CCNA2 (0.68) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL16001668 | 0.84 | CCNA2 (0.67) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL2069637 | 0.83 | CCNA2 (0.66) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL1164157 | 0.83 | CCNA2 (0.69) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL2068900 | 0.83 | CCNA2 (0.66) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784486 | 0.83 | CCNA2 (0.66) | CCNA2CDK2IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019405-A1 | PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-02-17 | — | — | WO | disclosed |