Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.83 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581587 | 0.93 | MRGPRX4 (0.73) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL31177977 | 0.91 | HIF1A (1.00) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL14758954 | 0.90 | FFAR1 (0.70) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL2185809 | 0.90 | FFAR1 (0.70) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL15458722 | 0.88 | HIF1A (0.67) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL16550428 | 0.87 | HIF1A (0.70) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL19696532 | 0.87 | HDAC8 (0.70) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL4748420 | 0.85 | HIF1A (0.68) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL22480946 | 0.85 | MRGPRX4 (1.00) | HIF1AHDAC8HDAC6MRGPRX4FFAR1 | |
| SCHEMBL10055040 | 0.84 | FFAR1 (0.68) | HIF1AMRGPRX4FFAR1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012048033-A2 | NOVEL COMPOSITIONS FOR INHIBITING VIRUS ENTRY AND PROMOTING VIROLYISIS, AND METHODS THEREOF | DREXEL UNIVERSITY (US) | 2012-04-12 | — | — | WO | disclosed |