Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL177128 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL360904 | 0.96 | — | — | |
| Acetic Acid SCHEMBL28340757 | 0.92 | FFAR3 (0.58) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL28108156 | 0.92 | — | — | |
| Acetic Acid SCHEMBL27522628 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28108158 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28591801 | 0.92 | — | — | |
| Acetone SCHEMBL4362729 | 0.82 | — | — | |
| Acetic Acid SCHEMBL29378511 | 0.82 | FFAR3 (0.88) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL29467734 | 0.82 | FFAR3 (0.88) | FFAR3LCKFYNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546309-B1 | ANTHRAPYRIDONE SULPHONIC ACID COMPOUNDS, PREPARATION AND USE THEREOF | UNIV DALIAN TECH (CN) | 2016-06-01 | — | — | EP | disclosed |
| EP-2682433-B1 | CARBONYLPROPYLSULFONYL ANTHRACENE PYRIDONE SULFONIC ACID COMPOUND AND PREPARATION METHOD AND USE THEREOF | UNIV DALIAN TECH (CN) | 2015-06-03 | — | — | EP | disclosed |
| US-8968453-B2 | Anthrapyridone sulfonic acid compounds and their preparation methods and applications | Zhuhai Ninestar Management Co., Ltd. (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8734580-B2 | Carbonyl propyl sulfuryl anthrapyridone sulfonic acid compounds and their preparation methods and applications | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2014-05-27 | — | — | US | disclosed |
| EP-2682433-A1 | CARBONYLPROPYLSULFONYL ANTHRACENE PYRIDONE SULFONIC ACID COMPOUND AND PREPARATION METHOD AND USE THEREOF | Dalian University Of Technology (CN) | 2014-01-08 | — | — | EP | disclosed |
| US-20130327248-A1 | ANTHRAPYRIDONE SULFONIC ACID COMPOUNDS AND THEIR PREPARATION METHODS AND APPLICATIONS | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2013-12-12 | — | — | US | disclosed |
| US-20130276667-A1 | CARBONYL PROPYL SULFURYL ANTHRAPYRIDONE SULFONIC ACID COMPOUNDS AND THEIR PREPARATION METHODS AND APPLICATIONS | Zhuhai Ninestar Management Co., Ltd. (CN) | 2013-10-24 | — | — | US | disclosed |
| EP-2546309-A1 | ANTHRAPYRIDONE SULPHONIC ACID COMPOUNDS, PREPARATION AND USE THEREOF | Dalian University Of Technology (CN) | 2013-01-16 | — | — | EP | disclosed |
| EP-1545889-B1 | IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS, PRINTER DRIVER, IMAGE PROCESSING METHOD AND COMPUTER-READABLE STORAGE MEDIUM | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-7576886-B2 | Image processing apparatus, image forming apparatus, printer driver, image processing method and computer-readable storage medium | RICOH COMPANY, LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| EP-1945455-A1 | IMAGE PROCESSING METHOD, COMPUTER-READABLE PROGRAM, IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS AND IMAGE FORMING SYSTEM | Ricoh Company, Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-20080123117-A1 | Image Processing Method, Computer-Readable Program, Image Processing Apparatus, Image Forming Apparatus and Image Forming System | RICOH COMPANY, LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1545889-A4 | IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS, PRINTER DRIVER, IMAGE PROCESSING METHOD AND COMPUTER-READABLE STORAGE MEDIUM | RICOH KK (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007052781-A1 | IMAGE PROCESSING METHOD, COMPUTER-READABLE PROGRAM, IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS AND IMAGE FORMING SYSTEM | RICOH COMPANY, LTD. (JP) | 2007-05-10 | — | — | WO | disclosed |
| US-20050200905-A1 | Image processing apparatus, image forming apparatus, printer driver, image processing method and computer-readable storage medium | RICOH COMPANY, LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-1545889-A1 | IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS, PRINTER DRIVER, IMAGE PROCESSING METHOD AND COMPUTER-READABLE STORAGE MEDIUM | Ricoh Company, Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004000563-A1 | IMAGE PROCESSING APPARATUS, IMAGE FORMING APPARATUS, PRINTER DRIVER, IMAGE PROCESSING METHOD AND COMPUTER-READABLE STORAGE MEDIUM | RICOH COMPANY, LTD. (JP) | 2003-12-31 | — | — | WO | disclosed |