Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210237 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| Hydrochloric Acid SCHEMBL1209788 | 0.99 | KDM4E (0.38) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL12880377 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL12880461 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL12880451 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL1210100 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| Hydrochloric Acid SCHEMBL1210386 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL1207855 | 0.88 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL17054262 | 0.86 | KDM4E (0.40) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA | |
| SCHEMBL1208419 | 0.84 | RAD52 (0.44) | SMN1; SMN2KDM4EALDH1A1ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110044899-A1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110044899-A1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | CBR3, ADRB3, HRH4 | SMN1; SMN2 3676/4885KDM4E 4623/4885ALDH1A1 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.