Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691880 | 1.00 | CD38 (0.31) | CD38 | |
| SCHEMBL2691704 | 0.86 | CD38 (0.31) | CD38 | |
| SCHEMBL1688656 | 0.85 | PLK1 (0.34) | — | |
| SCHEMBL5943402 | 0.81 | — | — | |
| SCHEMBL5942927 | 0.81 | — | — | |
| SCHEMBL1289113 | 0.81 | — | — | |
| SCHEMBL2341831 | 0.81 | PLK2 (0.35) | CD38 | |
| SCHEMBL2690159 | 0.80 | PLK2 (0.48) | — | |
| SCHEMBL2689784 | 0.80 | CYP1A2 (0.30) | — | |
| SCHEMBL2691936 | 0.80 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661268-A2 | INHIBITORS OF POLO-LIKE KINASE | Elan Pharmaceuticals Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| WO-2012048129-A2 | INHIBITORS OF POLO-LIKE KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |