⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637912 | 1.00 | — | — | |
| SCHEMBL2384 | 0.94 | — | — | |
| SCHEMBL27496585 | 0.89 | — | — | |
| SCHEMBL6276848 | 0.89 | — | — | |
| SCHEMBL14658831 | 0.89 | — | — | |
| SCHEMBL20420706 | 0.89 | — | — | |
| SCHEMBL27480483 | 0.89 | — | — | |
| SCHEMBL27971779 | 0.89 | — | — | |
| Pyridine SCHEMBL1048169 | 0.77 | — | — | |
| Magnesium Chloride Anhydrous SCHEMBL27971840 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392409-A1 | PYRAZINE COMPOUNDS AS IRREVERSIBLE INHIBITORS OF FLT3 | Biomea Fusion, Inc. (US) | 2024-07-03 | — | — | EP | claimed |
| CN-111574477-B | Synthesis method of amide compound | 湖南大学 | 2024-06-28 | — | — | CN | claimed |
| EP-4370506-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | Biomea Fusion, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| US-20240124467-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN-MLL INTERACTION | BIOMEA FUSION, INC. | 2024-04-18 | — | — | US | claimed |
| EP-4263542-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN-MLL INTERACTION | Biomea Fusion, Inc. (US) | 2023-10-25 | — | — | EP | claimed |
| WO-2023129667-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | BIOMEA FUSION, INC. (US) | 2023-07-06 | — | — | WO | claimed |
| WO-2023027966-A1 | PYRAZINE COMPOUNDS AS IRREVERSIBLE INHIBITORS OF FLT3 | BIOMEA FUSION, INC. (US) | 2023-03-02 | — | — | WO | claimed |
| CN-115504973-A | Benzisoxazole compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-23 | — | — | CN | claimed |
| CN-114853634-A | Nicotinyl alcohol ether derivative, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-08-05 | — | — | CN | claimed |
| WO-2022133064-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN-MLL INTERACTION | BIOMEA FUSION, INC. (US) | 2022-06-23 | — | — | WO | claimed |
| US-4668669-A | BACTERICIDES, MICROBIOCIDES, SYNERGISTINS | RHONE-POULENC SANTE (FR) | 1987-05-26 | — | — | US | claimed |
| US-4647559-A | ANTISECRETORY AND ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1987-03-03 | — | — | US | claimed |
| EP-0198918-A1 | BICYCLIC BENZO-OXY HETEROCYCLIC ETHERS AND THIOETHERS AS H 2?-RECEPTORS ANTAGONISTS | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1986-10-29 | — | — | EP | claimed |
| US-4612309-A | Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers | WILLIAM H. RORER, INC. (US) | 1986-09-16 | — | — | US | claimed |
| US-4590004-A | MICROBIOCIDES | RHONE-POULENC SANTE (FR) | 1986-05-20 | — | — | US | claimed |
| WO-1986002550-A1 | BICYCLIC BENZO-OXY HETEROCYCLIC ETHERS AND THIOETHERS AS H2-RECEPTORS ANTAGONISTS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1986-05-09 | — | — | WO | claimed |
| EP-0150192-A4 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-16 | — | — | EP | claimed |
| EP-0150192-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INT OVERSEAS (US) | 1985-08-07 | — | — | EP | claimed |
| WO-1984004247-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INT OVERSEAS (US) | 1984-11-08 | — | — | WO | claimed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | claimed |