SCHEMBL12894752

SCHEMBL12894752

CC(OC(=O)O)n1cc(F)c(N)nc1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 4/20 0.33
ALB P02768 1/20 0.33
DCK P27707 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12741728 0.83 EP300 (0.41) EP300ALB
SCHEMBL10137844 0.78 ADORA2A (0.38) EP300ALBDCK
SCHEMBL12894749 0.76 ALB (0.36) EP300ALBDCK
SCHEMBL12228265 0.76 ALB (0.36) EP300ALB
SCHEMBL1224511 0.72 ALB (0.34) EP300ALBDCK
SCHEMBL20998845 0.72 ALB (0.33) ALB
SCHEMBL13846339 0.71 ALB (0.34) EP300ALB
SCHEMBL12741722 0.70 EP300 (0.41) EP300ALB
SCHEMBL22139331 0.69 ALB (0.35) EP300ALB
SCHEMBL1739594 0.67 ALB (0.38) EP300ALBDCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011017540-A1 5-FLUOROPYRIMIDINONE DERIVATIVES DOW AGROSCIENCES LLC (US) 2011-02-10 WO disclosed