Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.63 |
| ▸ | CDK9 | P50750 | 5/20 | 0.43 |
| ▸ | CCNK | O75909 | 3/20 | 0.43 |
| ▸ | CDK14 | O94921 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.38 |
| ▸ | CDK17 | Q00537 | 1/20 | 0.38 |
| ▸ | CDK18 | Q07002 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088533 | 0.81 | CCNT1 (0.77) | CCNT1 | |
| SCHEMBL1192259 | 0.81 | CCNT1 (0.77) | CCNT1 | |
| SCHEMBL1192222 | 0.81 | CCNT1 (0.77) | CCNT1 | |
| SCHEMBL12889616 | 0.80 | CCNT1 (0.65) | CCNT1CDK9CCNK | |
| SCHEMBL16588570 | 0.79 | CCNT1 (0.78) | CCNT1CDK9CCNK | |
| SCHEMBL1192438 | 0.78 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL1192286 | 0.78 | CCNT1 (1.00) | CCNT1CDK9CCNKCDK14CDK1 | |
| SCHEMBL12850250 | 0.72 | CCNT1 (0.75) | CCNT1 | |
| SCHEMBL16588571 | 0.71 | CCNK (0.64) | CCNT1CDK9CCNK | |
| SCHEMBL1192004 | 0.70 | CCNT1 (0.77) | CCNT1CDK9CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012661-A1 | PYRIDINE AND PYRAZINE DERIVATIVES AS PROTEIN KINASE MODULATORS | NOVARTIS AG (CH) | 2011-02-03 | — | — | WO | disclosed |