⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231 | 0.71 | — | — | |
| SCHEMBL8420217 | 0.67 | — | — | |
| SCHEMBL28961020 | 0.61 | — | — | |
| Ammonia Solution, Strong SCHEMBL8716502 | 0.61 | — | — | |
| SCHEMBL28603693 | 0.61 | — | — | |
| Iodide SCHEMBL7745366 | 0.61 | — | — | |
| SCHEMBL28730437 | 0.61 | — | — | |
| SCHEMBL8796802 | 0.61 | — | — | |
| SCHEMBL2192827 | 0.61 | — | — | |
| SCHEMBL11113869 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170246191-A1 | 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. | 2017-08-31 | — | — | US | disclosed |
| US-9512165-B2 | 19-nor C3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof | SAGE THERAPEUTICS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9365611-B2 | 19-NOR neuroactive steroids and methods of use thereof | SAGE THERAPEUTICS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160108080-A1 | 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-20160083418-A1 | 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. | 2016-03-24 | — | — | US | disclosed |
| US-20120208278-A1 | INNATE IMMUNE SUPPRESSION ENABLES REPEATED DELIVERY OF LONG RNA MOLECULES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120178147-A1 | MICROBIAL CULTURES AND METHODS FOR ANAEROBIC BIOREMEDIATION | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2012-07-12 | — | — | US | disclosed |
| US-20110288524-A1 | Patient hydration method | RENALGUARD SOLUTIONS, INC. | 2011-11-24 | — | — | US | disclosed |
| US-7652134-B2 | Tumor suppression agents with reduced side effects; anticancer; antibacterial and antiviral; contacting the corresponding ester with an amine and a Lewis acid | CYLENE PHARMACEUTICALS, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| US-20090324536-A1 | ANTIMICROBIAL POLYMERS AND COATINGS | THE UNIVERSITY OF SOUTH DAKOTA (US) | 2009-12-31 | — | — | US | disclosed |