SCHEMBL12901717

SCHEMBL12901717

CCc1ccc(-c2cc3ncn(C)c(=O)c3c(NC(C)C)n2)cn1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SYK P43405 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233810 0.91 SYK (0.78) SYK
SCHEMBL1235815 0.89 SYK (0.79) SYK
SCHEMBL1235010 0.87 SYK (1.00) SYK
SCHEMBL1236177 0.87 SYK (1.00) SYK
SCHEMBL1233806 0.86 SYK (1.00) SYK
SCHEMBL1235537 0.86 SYK (1.00) SYK
SCHEMBL1236264 0.85 SYK (1.00) SYK
SCHEMBL1236002 0.85 SYK (1.00) SYK
SCHEMBL1236592 0.83 SYK (1.00) SYK
SCHEMBL1235814 0.83 SYK (1.00) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011014795-A2 COMPOUNDS AND COMPOSITIONS AS SYK KINASE INHIBITORS IRM LLC (BM) 2011-02-03 WO disclosed