Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903493 | 0.92 | DAO (0.40) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12864263 | 0.91 | DAO (0.42) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12903504 | 0.90 | DAO (0.40) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12903494 | 0.84 | DAO (0.44) | DAOKDM4EGAAPOLBMMP2 | |
| SCHEMBL12864271 | 0.83 | DAO (0.41) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12864273 | 0.82 | DAO (0.59) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12864272 | 0.82 | DAO (0.41) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL12864264 | 0.81 | DAO (0.54) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL1170831 | 0.78 | DAO (0.54) | DAOKDM4ELMNATP53L3MBTL1 | |
| SCHEMBL1171045 | 0.77 | DAO (0.50) | DAOKDM4ELMNATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017634-A2 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACORE INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2010017418-A1 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-11 | — | — | WO | disclosed |