SCHEMBL1290621

SCHEMBL1290621

Fc1c(F)c(F)c(-c2cc3cc4nc(cc5ccc(cc6nc(cc2[nH]3)C=C6)[nH]5)C=C4)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.38
▸ STAT1 P42224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28636010 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL30578376 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL28423403 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL29067564 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL28968623 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL30669205 0.98 STAT3 (0.38) STAT3STAT1
Hydrochloric Acid SCHEMBL1459232 0.98 STAT3 (0.38) STAT3STAT1
SCHEMBL30426898 0.98 STAT3 (0.38) STAT3STAT1
Hydrochloric Acid SCHEMBL5596540 0.97 STAT3 (0.37) STAT3STAT1
Hydrochloric Acid SCHEMBL28557253 0.97 STAT3 (0.37) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250189451-A1 METHOD AND PROBE FOR MONITORING OXYGEN STATUS IN LIVE MAMMALIAN CELLS UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2025-06-12 — — US claimed
US-12181414-B2 Method and probe for monitoring oxygen status in live mammalian cells UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2024-12-31 — — US claimed
CN-118561659-A Method for catalyzing molecular oxygen to oxidize cycloparaffin by porphyrin under visible light condensation condition 浙江工业大学 2024-08-30 — — CN claimed
CN-118420627-A Fluorescence enrichment tag, preparation method, visual guidance proteome analysis method and application of analysis method 复旦大学 2024-08-02 — — CN claimed
CN-118329955-A Nonmetallic embedded fullerene electron spin probe and application thereof in measurement of eutectic weak bonding strength 中国人民解放军国防科技大学 2024-07-12 — — CN claimed
CN-115155532-B Polyfluoroporphyrin covalent organic framework magnetic nanosphere and preparation method and application thereof 武汉工程大学 2024-04-26 — — CN claimed
CN-117645820-A Pressure sensitive paint capable of improving oxygen permeability and preparation and use methods thereof 中昊北方涂料工业研究设计院有限公司 2024-03-05 — — CN claimed
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 — — CN claimed
CN-117092080-A Oxygen sensing membrane, method for producing the same, and use thereof in detection of gaseous oxygen concentration 宁波大学 2023-11-21 — — CN claimed
CN-112912386-B Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2023-10-20 — — CN claimed
CN-112771129-A Colorimetric sensor formulations and uses thereof 都柏林三一学院 2021-05-07 — — CN claimed
CN-112730643-A Method and device for representing flavor of fermented bean curd based on visual fusion technology 江苏大学 2021-04-30 — — CN claimed
CN-108088821-B High-precision air film cooling efficiency testing method based on pressure sensitive paint 中国空气动力研究与发展中心高速空气动力研究所 2021-03-09 — — CN claimed
CN-111693691-A Polymer label based on porphyrin structure 天津华科泰生物技术有限公司 2020-09-22 — — CN claimed
CN-110951050-A Fluorine-substituted Zn/Co porphyrin-based conjugated organic polymer and preparation method and application thereof 武汉大学深圳研究院 2020-04-03 — — CN claimed
US-10011587-B2 Multivalent ligands targeting VEGFR THE METHODIST HOSPITAL SYSTEM (US) 2018-07-03 — — US claimed
EP-2373989-A1 OPTOCHEMICAL SENSOR ACTIVE ELEMENT, METHOD OF ITS PREPARATION AND USE Luxcel Biosciences Limited (IE) 2011-10-12 — — EP claimed
US-20110244592-A1 OPTOCHEMICAL SENSOR ACTIVE ELEMENT, METHOD OF ITS PREPARATION AND USE LUXCEL BIOSCIENCES LIMITED (IE) 2011-10-06 — — US claimed
WO-2010066273-A1 OPTOCHEMICAL SENSOR ACTIVE ELEMENT, METHOD OF ITS PREPARATION AND USE LUXCEL BIOSCIENCES LIMITED (IE) 2010-06-17 — — WO claimed
US-6575620-B1 Method and device for visually measuring structural fatigue using a temperature sensitive coating THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-06-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011587-B2 Multivalent ligands targeting VEGFR KDR, FLT4, FLT1 STAT3 721/4885STAT1 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback