Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305280 | 0.89 | TP53 (0.74) | TP53MAPTLMNABACE1CYP2C19 | |
| SCHEMBL12907698 | 0.88 | CYP2D6 (0.55) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL4665854 | 0.86 | BACE1 (0.60) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL12907704 | 0.86 | ABL1 (0.70) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL25482387 | 0.85 | TP53 (0.55) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL4666194 | 0.84 | TP53 (0.61) | TP53MAPTBACE1CYP2C19CYP1A2 | |
| SCHEMBL12907691 | 0.84 | CYP3A4 (0.58) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL5923900 | 0.84 | TRPV1 (0.65) | TP53MAPTLMNABACE1CYP2C19 | |
| SCHEMBL12907708 | 0.84 | BACE1 (0.57) | TP53MAPTLMNAPOLBBACE1 | |
| SCHEMBL12907685 | 0.82 | MAPT (0.58) | TP53MAPTLMNACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021524-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | IRM LLC (BM) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021524-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCERS | ABL1, BCR, MCL1 | TP53 15/4885MAPT 4166/4885LMNA 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.