Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.65 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801658 | 0.91 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL1802559 | 0.86 | TLR8 (0.71) | TLR8TLR7 | |
| SCHEMBL12909373 | 0.85 | TLR8 (0.73) | TLR8TLR7 | |
| SCHEMBL12619265 | 0.83 | TLR8 (0.76) | TLR8TLR7 | |
| SCHEMBL1589321 | 0.83 | TLR8 (0.76) | TLR8TLR7 | |
| SCHEMBL1802552 | 0.83 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL1806746 | 0.82 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL1801423 | 0.82 | TLR8 (0.75) | TLR8TLR7 | |
| SCHEMBL25687949 | 0.82 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL1588933 | 0.82 | TLR8 (0.66) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011022509-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VENTIRX PHARMACEUTICALS, INC. (US) | 2011-02-24 | — | — | WO | disclosed |